<i>ARID1B</i>-mediated disorders: Mutations and possible mechanisms

O-1: Thraputic Effect of Silymarin, Celecoxib and Exogenous Testosterone on Varicocele-Induced Disorders; Possible Mechanisms

Background Varicocele (VCL) is characterized by a progressive disorder which is defined by tortuosity of the pampiniform plexus veins that exerts bilateral impacts. 50-60 percent of males with infertility problems are suffering from VCL. Considering VCL-induced massive problems in human fertilizing potential, investigating different aspects of VCL-induced derangements is gaining considerable at...

Myeloproliferative disorders and its associated mutations

Myeloproliferative Neoplasm (MPN) are a clonal disorder in hematopoietic stem cells (HSC). MPN is categorized to 8 subclasses, including chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocytopenia (ET), primary myelofibrosis (PMF), systematic mastositosis (SM), chronic eosinophilic leukemia (CEL), chronic neutrophilic leukemia (CNL), and unclassified myelofibrosis disorde...

Possible regulatory mechanisms in the ovarian disorders.

Long-term investigation of prevalence of antiovarian antibodies in serum of girls and adolescent women confirm their significantly higher incidence in patients with primary amenorhea (PA), oligomenorhea and secondary amenorhea (OSA). Simultaneously, in association with ovarian disorders, significantly increased levels of gonadotropins, particularly FSH, LH and their ratio (FSH/LH) declare an ac...

Editorial: Leptin Resistance in Metabolic Disorders: Possible Mechanisms and Treatments

Epidemiology and possible mechanisms

Background. Many early epidemiologic studies reported an association between periodontal disease and cardiovascular disease. However, other studies found no association or nonsignificant trends. This report summarizes the evidence from epidemiologic studies and studies that focused on potential contributing mechanisms to provide a more complete picture of the association between periodontal and...